Integrative Treatment of the Pet with Cancer

November 17, 2012 on 10:45 am | In General Posts | Comments Off

Designing individualized treatment protocols for each person or pet with cancer, incorporating a proper diet, nutritional supplements, and other natural therapies offers a much better prognosis for the cancer patient. We now have large volumes of research to show exactly how these natural therapies work in killing cancer and extending the lives of cancer patients.

In my own practice, the average pet with cancer typically lives 1 ½-2 times longer than expected when placed on an integrative cancer protocol. Additionally, many pets with “incurable” cancers are cured from their cancers using an integrative approach to boost the pet’s immune system, kill cancer cells, reduce the spread of cancer, and detoxify the patient.

The world of integrative oncology offers much hope for the cancer patient. Integrative doctors are helping people and pets with cancer live longer lives and in many cases curing cancers that are still considered incurable by conventional medicine.

Goals-

Treat the pet not just the disease

Don’t forget there’s a pet attached to the tumor

Do what is necessary to give the pet the best chance for cure or long remission

No vaccines

Minimize chemicals (flea) and unnecessary medications

Natural Diet (Cancer Diet) Hippocrates said “Let food be your medicine.” Regardless of the kind of care chosen by the cancer patient, a proper cancer fighting diet is the foundation upon which other treatments are built.

Encourage “holistic” clients to do chemo/radiation when appropriate

Use Supplements

“No matter how much surgery you do to cut out cancer, or how much radiation you use to burn out cancer, or how much chemotherapy you use to poison cancer, if the patient’s immune system is not functioning properly, that patient will die from cancer.”

That statement, made by world-famous cancer expert Dr. Russell Blaylock in my book, The Natural Vet’s Guide to Preventing and Treating Cancer in Dogs, really says it all.

The questions are very simple: what are you doing now to make your conventional therapies more effective and reduce their side effects, and what will you do once your conventional therapies stop to prevent your cancer from coming back?

Supporting the cancer patient requires supplements to do the following:

Support/boost immune system

Supplements that fall into this category include medicinal mushrooms (Ganoderma lucidum, Agaricus bisporus, Agaricus blazei , A. brasiliensis, Trametes versicolor, Grifola frondosa, Inonotus obliquus, Lentinus edodes, Leucoagaricus americanus, Pleurotus ostreatus, Sparassis crispa, Cordyceps sinensis, and Coriolus versicolor) which contain a number of active ingredients including polysaccharides and protein complexes including beta glucans. These ingredients may help the cancer patient by inhibiting NF-κB activity (NF-κB is involved in inflammation, cell survival, and transformation of normal cells into cancer cells.) Mushrooms inhibit cell proliferation and cell cycle arrest at the G2/M phase of highly invasive human breast cancer cells and inhibit the expression of cell cycle regulatory genes (ANAPC2, ANAPC2, BIRC5, Cyclin B1, Cyclin H, CDC20, CDK2, CKS1B, Cullin 1, E2F1, KPNA2, PKMYT1 and TFDP1). Mushrooms also suppress metastasis inhibiting cell adhesion, cell migration, and cell invasion.

Detoxification (herbs and homeopathics)

Examples of supplements for detoxification include milk thistle (Holy Thistle, St. Mary’s Thistle) which contains silymarin, composed of three major flavolignans: silibinin (silybin,) silidyanin, and silychristin, as well as other compounds such as apigenin, histamine, oleic acid, stearic acid, palmitic acid, and myristic acid.

Silymarin has been shown to protect the liver from damage by various chemicals and functions as a liver-protective supplement by altering the outer liver cell membrane so that toxins cannot enter the cell. Silymarin inhibits the growth of certain human cancer lines in vitro and inhibits the 5-LOX pathway, reducing inflammation in the body. Finally, silymarin works as an antioxidant.

Silymarin also fights cancer by inhibiting intestinal beta-glucoronidase, modulating carcinogen metabolizing enzymes, and inhibiting epidermal growth factor receptor and kinases.

Kill cancer/reduce metastasis/reduce angiogenesis

An example (there are many supplements which are valuable here) includes:

Vitamin D3

Research shows that most people are severely deficient in Vitamin D, even those who receive sunlight exposure. It is recommended that vitamin D3 should be a supplement most people take for its numerous health benefits, including cancer prevention. Vitamin D kills cancer by promoting cell differentiation and supporting apoptosis (normal programmed cell death), as well as helping to prevent metastases and angiogenesis (new blood vessel formation needed for cancer to grow and spread.)

Antioxidants

Since the 1970s, 280 peer-reviewed in vitro and in vivo studies, including 50 human studies involving 8,521 patients, 5,081 of whom were given nutrients, have consistently shown that non-prescription antioxidants and other nutrients do not interfere with therapeutic modalities (chemo/radiation) for cancer. Furthermore, they enhance the killing of therapeutic modalities for cancer, decrease their side effects, and protect normal tissue. In 15 human studies, 3,738 patients who took non-prescription antioxidants and other nutrients actually had increased survival.

Altern Ther Health Med, 2007 Jan-Feb;13(1):22-8.

Lesson: Properly chosen antioxidants will maximize the ability of radiation to kill cancerous cells while decreasing the harm radiation therapy can do to normal cells

Fatty Acids

Fish oil (vs flax)

A higher omega-3:omega-6 ratio ((n-3)):(n-6) ratio) may reduce the risk of cancer.

Omega-3 fatty acids (primarily eicosapentanoic acid (EPA) and docosahexaneoic acid (DHA)) have been shown to retard the growth of cancer in the lab and in animal experiments, and inhibit tumor development and metastasis.

Fish oils have anti-proliferative effects at high doses, reducing the growth of cancer cells

EPA and DHA inhibit the pro-inflammatory enzyme cyclooxygenase 2 (COX 2,) an enzyme that leads to inflammation and therefore promotes cancer.

Studies suggest that chronic activation of a pro-inflammatory gene switch (transcription factor) called Nf-KappaB is important to cancer cell survival. NFKB has also been found to play important roles in all stages of cancer development. Studies show that omega-3 fatty acids from fish oil suppress activation of NFKB.

Ground flax seed (but not flax oil) provides a healthy dose of lignans. Lignans also have non-hormonal actions including antioxidant and anti-angiogenic effects. Studies have shown significant reductions in breast cancer risk in women with the highest versus the lowest quartile of urinary enterolactone excretion, serum enterolactone levels, or lignan intake. Flaxseed also has a high concentration of α-linolenic acid which has been shown in animal and human studies to be protective against breast cancer.

Working with a veterinarian skilled in integrative medicine is the best way to ensure that your pet is receiving the correct supplements at the correct dosage.

Continue to visit my website as several supplements I have created to help my cancer patients will be available for sell through my new ecommerce site!

Is it OK to Use Supplements if the Pet is On Chemo or Radiation Treatment?

November 5, 2012 on 7:53 pm | In General Posts | Comments Off

While controversial among conventional doctors, the answer is usually Yes!

Supplements, including antioxidants, generally do NOT interfere with chemotherapy or radiation but rather enhance the effectiveness of these therapies and minimize side effects from them.

In general, balanced antioxidants, rather than megadoses of specific antioxidants (especially vitamins and minerals,) tend to work the best and are safest to use.

To be safe, make sure any supplements you use are done under the care of a holistic veterinarian. There is a greater discussion of this important topic in my book, The Natural Vet’s Guide to Preventing and Treating Cancer in Dogs, pages 110-113.

Note:

Since the 1970s, 280 peer-reviewed in vitro and in vivo studies, including 50 human studies involving 8,521 patients, 5,081 of whom were given nutrients, have consistently shown that non-prescription antioxidants and other nutrients do not interfere with therapeutic modalities (chemo/radiation) for cancer. Furthermore, they enhance the killing of therapeutic modalities for cancer, decrease their side effects, and protect normal tissue. In 15 human studies, 3,738 patients who took non-prescription antioxidants and other nutrients actually had increased survival.

Altern Ther Health Med, 2007 Jan-Feb;13(1):22-8.

Lesson: Properly chosen antioxidants will maximize the ability of radiation to kill cancerous cells while decreasing the harm radiation therapy can do to normal cells.

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